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Studies of human genetic history using the Y chromosome

Part 1. Genetics

1.1. Genetic Variation and Evolution

Short Specialist Review

  1. Mark A. Jobling

Published Online: 15 APR 2005

DOI: 10.1002/047001153X.g101308

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Jobling, M. A. 2005. Studies of human genetic history using the Y chromosome. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 1:1.1:4.

Author Information

  1. University of Leicester, Leicester, UK

Publication History

  1. Published Online: 15 APR 2005

Abstract

Escape from recombination makes the Y chromosome a useful tool for studying human genetic history. A unique phylogeny of Y haplogroups has been constructed using binary markers such as SNPs (single nucleotide polymorphisms), and diversity within haplogroups can be analyzed using multiple microsatellites. The time-depth of the phylogeny and geographical distribution of the deepest-rooting haplogroups are compatible with a recent African origin for modern humans. Haplogroup distributions are highly geographically differentiated, which allows past population movements to be studied, and sex-biased admixture to be recognized.

Keywords:

  • Y chromosome;
  • haplotype;
  • genetic drift;
  • population;
  • selection;
  • SNP;
  • microsatellite;
  • admixture;
  • patrilocality