Genetic signatures of natural selection
Part 1. Genetics
1.1. Genetic Variation and Evolution
Short Specialist Review
Published Online: 15 OCT 2004
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Przeworski, M. and Bustamante, C. D. 2004. Genetic signatures of natural selection. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 1:1.1:7.
- Published Online: 15 OCT 2004
Molecular population genetic data carry information about the evolutionary forces that have shaped the history of the species and, in particular, about past adaptations. Here, we review how nucleotide sequence variation within and between species can be used to detect and characterize natural selection. We provide a brief description of tests of neutrality for various types of data, detail the limitations of current methods, and summarize recent theoretical advances that may be important in moving this growing field forward.
- natural selection;
- tests of neutrality;