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Studies of human genetic history using mtDNA variation

Part 1. Genetics

1.1. Genetic Variation and Evolution

Short Specialist Review

  1. Antonio Torroni,
  2. Chiara Rengo

Published Online: 15 APR 2005

DOI: 10.1002/047001153X.g101314

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Torroni, A. and Rengo, C. 2005. Studies of human genetic history using mtDNA variation. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 1:1.1:5.

Author Information

  1. University of Pavia, Pavia, Italy

Publication History

  1. Published Online: 15 APR 2005

Abstract

Current studies of human mitochondrial DNA have revealed that the dissection of its variation into smaller and younger subhaplogroups is an essential step in the identification of spatial frequency patterns, and that mass screening of a limited number of markers identified using complete mtDNA sequences is a very efficient strategy for inferring features of human genetic history.

Keywords:

  • mitochondrial DNA variation;
  • human origin and evolution;
  • human population genetics;
  • haplogroups;
  • phylogeography;
  • Native American origin;
  • colonization of Europe