Measuring variation in natural populations: a primer
Part 1. Genetics
1.1. Genetic Variation and Evolution
Basic Techniques and Approaches
Published Online: 15 JUL 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Harpending, H. 2005. Measuring variation in natural populations: a primer. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 1:1.1:10.
- Published Online: 15 JUL 2005
In this brief primer, I will first discuss common kinds of data sources appropriate for measuring variation and then describe statistical computations appropriate to each. With one exception all the methods I discuss are equivalent in the sense that they estimate average coalescence times of pairs of marker loci chosen from a population.
- genetic diversity;
- mean pairwise difference;
- short tandem repeats;
- segregating sites