Preimplantation genetic diagnosis for chromosome abnormalities
Part 1. Genetics
Short Specialist Review
Published Online: 15 JUL 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Munné, S. 2005. Preimplantation genetic diagnosis for chromosome abnormalities. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics.
- Published Online: 15 JUL 2005
Preimplantation genetic diagnosis (PGD) is the earliest form of prenatal diagnosis and has been used in over 5000 infertile patient procedures to improve pregnancy outcome for in vitro fertilization (IVF). PGD has also been used to limit spontaneous abortions and chromosomally unbalanced or aneuploid offspring in patients of advanced maternal age or carriers of translocations or other chromosome abnormalities.
- recurrent miscarriages;
- recurrent pregnancy loss;
- down syndrome;