Epigenetic variation: amount, causes, and consequences
Part 1. Genetics
Published Online: 15 DEC 2006
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
de la Casa-Esperón, E. and Sapienza, C. 2006. Epigenetic variation: amount, causes, and consequences. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 1:1.3.
- Published Online: 15 DEC 2006
Epigenetic variation is the result of biochemical and spatial modifications that affect the function of chromosomes. The diversity of phenotypes that we observe in all organisms is the result of both genetic and epigenetic variation. Unveiling the “epigenetic code” is challenging because of the diversity of mechanisms and the vast scale of epigenetic variation. Nevertheless, an increasing number of studies indicate that epigenetic variation has an important influence on many phenotypes, especially in human disorders.
- epigenetic variation;
- DNA methylation;
- phenotypic variation;
- X-chromosome inactivation;
- allelic variation in gene expression;
- epigenetic inheritance;
- chromatin modifications