Evolution of genomic imprinting in mammals
Part 1. Genetics
Short Specialist Review
Published Online: 15 NOV 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Spencer, H. G. 2005. Evolution of genomic imprinting in mammals. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics.
- Published Online: 15 NOV 2005
Genomic imprinting is an evolutionary paradox because it seems at first glance to be disadvantageous: the monoallelic expression it entails means that recessive deleterious mutations cannot be masked. Several hypotheses seek to resolve the paradox, and the strengths and weaknesses of the most plausible of these – ovarian time bomb, genomic conflict, differential selection on males and females – are discussed.
- genetic conflict;
- ovarian time bomb;
- prevention of parthenogenesis;
- differential selection on males and females