Algorithmic improvements in gene mapping
Part 1. Genetics
1.4. Gene Mapping
Short Specialist Review
Published Online: 15 JUL 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Abecasis, G. R. and Zhao, Y. 2005. Algorithmic improvements in gene mapping. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 1:1.4:52.
- Published Online: 15 JUL 2005
The analysis of human gene mapping data presents daunting computational challenges. Improvements in laboratory technology have motivated the development and refinement of increasingly sophisticated algorithms for the analysis of human pedigrees. We review and summarize some of the more important developments, and present a short history of the software packages that are now in widespread use in human gene mapping studies.
- gene-mapping algorithms;
- computational methods;
- human pedigrees;
- stochastic methods