Adeno-associated viral vectors: depend(o)ble stability
Part 1. Genetics
1.7. Gene Therapy
Short Specialist Review
Published Online: 15 JUL 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Snyder, R. O. 2005. Adeno-associated viral vectors: depend(o)ble stability. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 1:1.7:97.
- Published Online: 15 JUL 2005
Recombinant adeno-associated viral (rAAV) vectors can mediate the safe and long-term correction of genetic diseases in animal models following a single administration, and have been shown to persist and are safe in humans following delivery to lung, sinus, skeletal muscle, brain, and liver. The physiochemical properties of rAAV vector virions are amenable to industry-accepted manufacturing methodologies, long-term storage, and direct in vivo administration.
- adeno-associated virus;
- gene therapy;
- gene transfer;