Gene transfer to the skin
Part 1. Genetics
1.7. Gene Therapy
Basic Techniques and Approaches
Published Online: 15 APR 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Gagnoux-Palacios, L., Spirito, F. and Meneguzzi, G. 2005. Gene transfer to the skin. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 1:1.7:103.
- Published Online: 15 APR 2005
The transplantation of autologous artificial epithelia expressing recombinant genes, and direct transfer of DNA to the skin represent potential therapeutic approaches for a local or systemic delivery of active molecules. Successful cutaneous gene therapy trials require development of protocols for efficient gene transfer to epidermal stem cells, and information about the host immune response to the recombinant polypeptides produced by the delivered genes.
- transplantable epithelia