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Linking DNA to production: the mapping of quantitative trait loci in livestock

Part 2. Genomics

2.2. Mapping

Introductory Review

  1. Stephen S. Moore,
  2. Christiane Hansen,
  3. Changxi Li

Published Online: 15 APR 2005

DOI: 10.1002/047001153X.g202106

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Moore, S. S., Hansen, C. and Li, C. 2005. Linking DNA to production: the mapping of quantitative trait loci in livestock. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.2:10.

Author Information

  1. University of Alberta, Edmonton, AB, Canada

Publication History

  1. Published Online: 15 APR 2005

Abstract

The concept that quantitative variation is controlled by an infinite number of genes was a widely accepted hypothesis until the 1980s. The more recent concept of a few genes of moderate to large effect underlying quantitative variation is integral to our ability to detect genes affecting quantitative trait loci (QTL). This latter hypothesis has gained credence owing to the success of QTL mapping studies in multiple livestock species including cattle, sheep, swine, and chickens. A large number of QTL have been mapped for a variety of traits in livestock species. Only very few genes underlying QTL have, however, been identified to date. Methodologies are being developed that will increase our ability to identify the genes underlying QTL. This chapter gives an overview of the work that has been done to map QTL in cattle, swine, sheep, and chickens.

Keywords:

  • quantitative trait loci;
  • mapping;
  • livestock;
  • cattle;
  • swine;
  • sheep;
  • chicken