The Happy mapping approach
Part 2. Genomics
Short Specialist Review
Published Online: 15 JUL 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Galibert, F. 2005. The Happy mapping approach. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.2:22.
- Published Online: 15 JUL 2005
“Happy mapping” is an in vitro genome mapping method for type 1 and 2 markers that offers several advantages over the RH method. However, it is highly dependent on a whole-genome amplification step that till now has been difficult to realize given the very small amount of starting DNA. In this article, advantages and possible future developments are discussed in light of the difficulties inherent in the method.
- Happy mapping;
- RH mapping;
- whole-genome amplification;
- degenerated PCR;