Standard Article

Digital karyotyping: a powerful tool for cancer gene discovery

Part 2. Genomics

2.2. Mapping

Short Specialist Review

  1. Hai Yan,
  2. Darell Bigner

Published Online: 15 JUL 2006

DOI: 10.1002/047001153X.g202315

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Yan, H. and Bigner, D. 2006. Digital karyotyping: a powerful tool for cancer gene discovery. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.2.

Author Information

  1. Duke University Medical Center, Durham, NC, US

Publication History

  1. Published Online: 15 JUL 2006

Abstract

Digital karyotyping is a genome-wide approach that is designed to provide a global genomic content profiling of cells at high resolution. In cancer cells, knowledge of gene-specific genetic content alterations has the power to expedite the process of cancer gene discovery.

Keywords:

  • genomic alteration;
  • gene dosage;
  • digital karyotyping