Standard Article

Genome assembly

Part 2. Genomics

2.3. The Human Genome

Specialist Review

  1. Michael C. Wendl,
  2. John W. Wallis,
  3. Shiaw-Pyng Yang,
  4. Asif T. Chinwalla,
  5. LaDeana W. Hillier

Published Online: 15 JAN 2005

DOI: 10.1002/047001153X.g203206

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Wendl, M. C., Wallis, J. W., Yang, S.-P., Chinwalla, A. T. and Hillier, L. W. 2005. Genome assembly. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.3:25.

Author Information

  1. Washington University, St. Louis, MO, USA

Publication History

  1. Published Online: 15 JAN 2005

Abstract

We review the two approaches used for sequencing the human genome: whole genome shotgun and clone by clone. In particular, we describe the individual assembly strategies and summarize their results. The scientific community's ongoing assessment of these assemblies is also discussed.

Keywords:

  • genome assembly;
  • whole genome shotgun;
  • clone-by-clone;
  • sequence repeats