Comparisons with primate genomes
Part 2. Genomics
2.3. The Human Genome
Short Specialist Review
Published Online: 15 JAN 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Rocchi, M. and Archidiacono, N. 2005. Comparisons with primate genomes. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.3:32.
- Published Online: 15 JAN 2005
Molecular cytogenetic tools, whole-chromosome paints in particular, have been extensively used to disclose changes that have shaped the karyotype organization of primates. In addition, detailed marker order arrangement defined by using appropriate BAC and PAC probes have revealed the relatively frequent occurrence of an unprecedented phenomenon: the centromere repositioning during evolution. Remains of evolutionary inactivated centromeres appears to play a key role in the emergence of neocentromeres in human clinical cases.
- karyotype evolution;
- genome comparison;
- centromere repositioning