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The C. elegans genome

Part 2. Genomics

2.4. Model Organisms: Functional and Comparative Genomics

Short Specialist Review

  1. Jonathan Hodgkin

Published Online: 15 OCT 2004

DOI: 10.1002/047001153X.g204309

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Hodgkin, J. 2004. The C. elegans genome. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.4:44.

Author Information

  1. University of Oxford, Oxford, UK

Publication History

  1. Published Online: 15 OCT 2004

Abstract

The genome of the nematode Caenorhabditis elegans has been completely sequenced and subjected to extensive analysis. The 100 Mb genome includes almost 20 000 protein-coding genes and over 1000 structural and regulatory RNA genes. Unusual features of the genome and systematic approaches to its functional analysis are described and discussed.

Keywords:

  • genome;
  • Caenorhabditis elegans;
  • nematode;
  • gene number;
  • operons;
  • trans-splicing;
  • RNA interference