Comparative sequencing of vertebrate genomes
Part 2. Genomics
2.4. Model Organisms: Functional and Comparative Genomics
Short Specialist Review
Published Online: 15 JAN 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Portnoy, M. E. and Green, E. D. 2005. Comparative sequencing of vertebrate genomes. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.4:48.
- Published Online: 15 JAN 2005
The areas of large-scale DNA sequencing and sequence analysis are undergoing a rapid metamorphosis, as priorities shift from generating genome sequences for a select group of reference species to interpreting the information encoded therein. Comparison of the human genome sequence with that of other vertebrates has emerged as a critical component of this interpretative process. Newly developed experimental and computational methods are providing more powerful approaches for comparative sequence analyses, and in turn, these are being used for systematically unraveling the complexities of vertebrate genomes.
- genome sequencing;
- comparative genomics;
- genome analysis;
- genome annotation