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Eukaryotic parasite genome projects

Part 2. Genomics

2.5. Bacteria and Other Pathogens

Introductory Review

  1. Neil Hall

Published Online: 15 JAN 2005

DOI: 10.1002/047001153X.g205105

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Hall, N. 2005. Eukaryotic parasite genome projects. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.5:50.

Author Information

  1. The Institute for Genomic Research, Rockville, MD, USA

Publication History

  1. Published Online: 15 JAN 2005

Abstract

Genome sequence data is transforming the field of parasitology, and is proving to be a leading technology in the hunt for new drugs and vaccines for some of the most serious diseases affecting mankind. In this chapter, I will describe some of the key scientific contributions made by the genome projects and draw on some specific examples in protist parasites such as genetics in Trypanosome brucei, the discovery of polycistronic transcription Leishmania major, and the evolution of the apicoplast in Plasmodium falciparum.

Keywords:

  • parasites;
  • genomics;
  • plasmodium;
  • trypanosome;
  • leishmaina;
  • evolution;
  • vaccine;
  • drug target;
  • apicoplast