Part 2. Genomics
2.5. Bacteria and Other Pathogens
Short Specialist Review
Published Online: 15 JUL 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Weinstock, G. 2005. Spirochete genomes. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.5:60.
- Published Online: 15 JUL 2005
Spirochetes are a group of bacteria with a common threadlike morphology. Nevertheless, these organisms show great genomic diversity, ranging in size from 1 to over 4 Mb and in chromosome structure from the simple bacterial circular chromosome to complex collections of linear and circular chromosomes. The gene content of pathogenic spirochetes often shows few of the virulence factors found in the more extensively studied Proteobacteria or gram-positive bacteria. This may reflect the significant evolutionary distance from spirochetes to these other microbes as well as different strategies of infection.
- Lyme disease;