Avoiding stratification in association studies
Part 2. Genomics
Short Specialist Review
Published Online: 15 JAN 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Devlin, B. and Roeder, K. 2005. Avoiding stratification in association studies. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.6:75.
- Published Online: 15 JAN 2005
In the study of complex disease, separating causal from confounded factors is a challenge for genetic epidemiologists. Population structure can be an important source of confounding. In the context of population samples, the tools useful for overcoming the effects of population structure are described in terms of experimental design and statistical analysis.
- genomic control;
- structured association;
- population substructure;