Using ESTs for genome annotation – predicting the transcriptome
Part 2. Genomics
2.7. ESTs: Cancer Genes and the Anatomy Project
Published Online: 15 JUL 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Eyras, E. 2005. Using ESTs for genome annotation – predicting the transcriptome. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.7:81.
- Published Online: 15 JUL 2005
Expressed sequence tags (ESTs) provide a quick and cost-effective way to obtain information about the collection of expressed genes in a genome. They can also provide information about the expression of genes, alternative splicing, polymorphisms, and untranslated regions, complementing other standard methods of annotation and ab initio gene prediction. Here we describe some of the advantages and problems of the usage of ESTs for genome annotation, emphasizing their utility for describing alternative splicing.
- automatic annotation;
- expressed sequences;
- alternative splicing