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EST resources, clone sets, and databases

Part 2. Genomics

2.7. ESTs: Cancer Genes and the Anatomy Project

Specialist Review

  1. Janet F. Kelso

Published Online: 15 OCT 2004

DOI: 10.1002/047001153X.g207210

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Kelso, J. F. 2004. EST resources, clone sets, and databases. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.7:80.

Author Information

  1. University of the Western Cape, Bellville, South Africa

Publication History

  1. Published Online: 15 OCT 2004

Abstract

The large number of expressed sequence tags (ESTs) in public sequence databases has been invaluable in the identification of novel genes and in the production of expression maps and functional annotation of a large number of genomes. This chapter will provide an insight into the public EST repositories, including both those that store raw, unprocessed ESTs and those in which the redundant and error-prone ESTs are processed to yield gene indices. In addition, information will be provided about the consortia and commercial companies that generate and distribute the cDNA clone sets, which are the reagents for laboratory expression studies.

Keywords:

  • EST;
  • clone;
  • dbEST;
  • Unigene;
  • I.M.A.G.E.