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Microarrays: an overview

Part 2. Genomics

2.8. Expression Profiling

Introductory Review

  1. Jörg D. Hoheisel

Published Online: 15 JUL 2005

DOI: 10.1002/047001153X.g208103

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Hoheisel, J. D. 2005. Microarrays: an overview. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.8:90.

Author Information

  1. Deutsches Krebsforschungszentrum, Heidelberg, Germany

Publication History

  1. Published Online: 15 JUL 2005

Abstract

Microarrays have become a tool that is synonymous to modern molecular biology. From beginnings that were aimed at the high-throughput sequencing of the human genome, a wide variety of different technology platforms emerged, on which an even larger number of assay formats are performed. Currently, the technology is in a state of transition. The initial developmental phase is finished, with part of the technology established to a degree that processes are on the brink of routine application. Simultaneously, however, new applications and technical advances emerge continuously, which require further development and evaluation, also moving into fields other than the analysis of nucleic acids.

Keywords:

  • hybridization;
  • oligonucleotides;
  • in situ synthesis;
  • DNA chip;
  • microarray;
  • expression profiling;
  • functional analysis