The promise of gene signatures in cancer diagnosis and prognosis
Part 2. Genomics
2.8. Expression Profiling
Published Online: 15 JUL 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Sung, J. C., Lee, A. Y. and Yeatman, T. J. 2005. The promise of gene signatures in cancer diagnosis and prognosis. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.8:96.
- Published Online: 15 JUL 2005
Gene-expression profiling is a relatively new technology that has promise for developing mathematical models that might be useful in predicting diagnoses and prognoses for a number of different cancer types. While the promise of this approach has not yet been realized, there is accumulating evidence that this approach is feasible. Extensive validation of all molecular classifiers with large independent test sets will be necessary prior to clinical application.
- gene profiling;
- gene signature