Creating and hybridizing spotted DNA arrays
Part 2. Genomics
2.8. Expression Profiling
Published Online: 15 NOV 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Yang, I. V. 2005. Creating and hybridizing spotted DNA arrays. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.8:91.
- Published Online: 15 NOV 2005
DNA microarray analysis has become the most widely used technique for the study of gene-expression patterns on a genomic scale. Microarray analysis is a complex, multistep technique involving array fabrication, labeling, hybridization, and data analysis. This review attempts to capture some of the most significant events in the evolution of spotted microarray technology, and gives a brief overview of where the field is today.
- complementary DNA (cDNA);
- gene expression analysis;
- two-color hybridizations;
- transcription profiling