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Protein microarrays as an emerging tool for proteomics

Part 2. Genomics

2.8. Expression Profiling

Short Specialist Review

  1. Ji Qiu,
  2. Sam Hanash

Published Online: 15 JUL 2005

DOI: 10.1002/047001153X.g208311

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Qiu, J. and Hanash, S. 2005. Protein microarrays as an emerging tool for proteomics. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.8:100.

Author Information

  1. Fred Hutchinson Cancer Research Center, Seattle, WA, USA

Publication History

  1. Published Online: 15 JUL 2005

Abstract

The emerging technology of protein microarrays has a far-reaching potential to meet the needs for measuring not just the abundance of protein constituents but also their functional states and their interactions with other biomolecules, with the requisite high throughput and high sensitivity. While protein microarrays still present some challenging problems, recent progress makes it likely that it will be possible soon to interrogate proteins at a proteome scale, using protein microarrays, analogous to DNA microarrays, thus making a substantial impact on biomedical research.

Keywords:

  • protein microarray;
  • protein profiling;
  • antibody microarray;
  • proteome;
  • disease proteomics;
  • biomarker;
  • protein–protein interaction