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Seven years of yeast microarray analysis

Part 2. Genomics

2.8. Expression Profiling

Short Specialist Review

  1. Gavin Sherlock1,
  2. Paul T. Spellman2

Published Online: 15 JUL 2005

DOI: 10.1002/047001153X.g208312

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Sherlock, G. and Spellman, P. T. 2005. Seven years of yeast microarray analysis. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.8:97.

Author Information

  1. 1

    Stanford University, Stanford, CA, USA

  2. 2

    Lawrence Berkeley Laboratory, Berkeley, CA, USA

Publication History

  1. Published Online: 15 JUL 2005

Abstract

Since the advent of microarray technology in the mid-1990s, and finishing of the complete genome sequence of the yeast Saccharomyces cerevisiae in 1996, yeast has been at the forefront of genomic biology. In this article, we review the uses of microarrays to investigate yeast biology, and the wide range of applications that they have been used for. While, typically, people think of microarrays for generating large-scale expression measurements, we discuss several different experimental approaches that have used microarrays to probe almost every facet of a living yeast cell.

Keywords:

  • yeast;
  • microarray;
  • genomics;
  • bioinformatics;
  • Saccharomyces cerevisiae;
  • transcription;
  • expression;
  • gene regulation;
  • genetic networks