Standard Article

Tissue microarrays

Part 2. Genomics

2.8. Expression Profiling

Short Specialist Review

  1. Ronald Simon,
  2. Martina Mirlacher,
  3. Guido Sauter

Published Online: 15 JUL 2005

DOI: 10.1002/047001153X.g208315

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Simon, R., Mirlacher, M. and Sauter, G. 2005. Tissue microarrays. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 2:2.8:101.

Author Information

  1. University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Publication History

  1. Published Online: 15 JUL 2005

Abstract

Tissue microarrays (TMAs) allow for simultaneous analysis of thousands of well-characterized tissues and have, therefore, become a standard research tool for tissue-based studies. All types of in situ analysis can be applied to tissue microarrays, including immunohistochemistry, fluorescence in situ hybridization, and RNA in situ hybridization. The TMA technology thus enables highly standardized, fast, and affordable translational research studies of unprecedented scale that substantially facilitate translational research.

Keywords:

  • TMA;
  • tissue microarray;
  • immunohistochemistry;
  • in situ tissue analysis;
  • translational research;
  • drug discovery