Protein interactions in cellular signaling
Part 3. Proteomics
3.3. Mapping of Biochemical Networks
Published Online: 15 APR 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Pawson, T. 2005. Protein interactions in cellular signaling. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 3:3.3:34.
- Published Online: 15 APR 2005
Protein–protein interactions provide a fundamental mechanism through which cellular regulatory systems are organized, and specificity is imposed during signal transduction. Furthermore, the association of proteins into larger complexes supports the formation of more extended biochemical pathways and interaction networks that link and integrate different aspects of cellular behavior. The molecular principles that underlie protein–protein interactions also explain the ability of proteins to recognize specific phospholipids, nucleic acids, and second messengers, and, therefore, define a general theme in proteomics and cell biology.
- protein–protein interactions;
- signal transduction