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Energy transfer–based approaches to study G protein–coupled receptor dimerization and activation

Part 3. Proteomics

3.3. Mapping of Biochemical Networks

Short Specialist Review

  1. Ralf Jockers1,
  2. Michel Bouvier2,
  3. Stefano Marullo1

Published Online: 15 APR 2005

DOI: 10.1002/047001153X.g303315

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Jockers, R., Bouvier, M. and Marullo, S. 2005. Energy transfer–based approaches to study G protein–coupled receptor dimerization and activation. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 3:3.3:43.

Author Information

  1. 1

    Institut Cochin, Paris, France

  2. 2

    Université de Montréal, Montréal, QC, Canada

Publication History

  1. Published Online: 15 APR 2005

Abstract

During the past several years, energy transfer–based techniques have become quite popular to study G protein–coupled receptors and the dynamic processes that follow their activation. This review will highlight a number of important biological questions in the field of GPCR biology that have been addressed using these approaches.

Keywords:

  • dimerization;
  • energy transfer;
  • receptor;
  • G protein;
  • maturation;
  • FRET;
  • BRET;
  • conformational changes