Analyzing proteomic, genomic and transcriptomic elemental compositions to uncover the intimate evolution of biopolymers
Part 3. Proteomics
3.3. Mapping of Biochemical Networks
Short Specialist Review
Published Online: 15 APR 2006
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Baudouin-Cornu, P. and Bragg, J. G. 2006. Analyzing proteomic, genomic and transcriptomic elemental compositions to uncover the intimate evolution of biopolymers. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 3:3.3.
- Published Online: 15 APR 2006
The main elemental constituents of living organisms are subjected to biogeochemical cycles that result in both temporal and spatial variation in their abundance. Since organisms have to find their molecular constituents in the environment, this variability may affect the synthesis of biopolymers, in a manner that depends on their atomic (elemental) composition. For example, a biopolymer that is rich in a particular element may become more difficult to synthesize when that element is scarce. Indeed, several studies have now demonstrated that nutritional constraints can shape the evolution of biopolymers specifically in relation to their atomic composition; that is, at a more intimate scale than amino acid or base composition. We discuss these studies, and propose that the increasing availability of data on genomes, proteomes, and RNAs be exploited to study adaptive imprints in the atomic composition of biopolymers, and the factors driving these adaptations.
- elemental composition;
- atomic composition;
- biopolymer evolution;
- GC content;
- molecular evolution