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High content screening

Part 3. Proteomics

3.4. Functional Proteomics

Short Specialist Review

  1. D. Lansing Taylor,
  2. Kenneth A. Giuliano

Published Online: 15 APR 2005

DOI: 10.1002/047001153X.g304314

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Taylor, D. L. and Giuliano, K. A. 2005. High content screening. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 3:3.4:52.

Author Information

  1. Cellumen, Inc., Pittsburgh, PA, USA

Publication History

  1. Published Online: 15 APR 2005

Abstract

High Content Screening (HCS) has emerged as a powerful platform technology that is being used to “industrialize” cell biology; especially in academic research and drug discovery. Information on the distribution, in time and space, as well as the activity of cellular constituents is helping to define the functions of proteins and other critical cellular components. The ability of these methods to be automated and run at high throughput will revolutionize the analysis of protein function using cell biology.

Keywords:

  • cells;
  • cellomics;
  • high content screening;
  • fluorescence;
  • reagents;
  • microscopy;
  • imaging and informatics