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siRNA approaches in cell biology

Part 3. Proteomics

3.4. Functional Proteomics

Basic Techniques and Approaches

  1. Alexandra Gampel,
  2. Harry Mellor

Published Online: 15 APR 2005

DOI: 10.1002/047001153X.g304407

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Gampel, A. and Mellor, H. 2005. siRNA approaches in cell biology. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 3:3.4:60.

Author Information

  1. University of Bristol, Bristol, UK

Publication History

  1. Published Online: 15 APR 2005

Abstract

The success of the genome sequencing projects has given us access to the genetic identities of a wide range of organisms. Clearly, the greatest challenge now is to make use of this wealth of information and, specifically, to associate genes with physiological functions. In one of the bizarre coincidences that litter the history of scientific research, this challenge has emerged at the same time as a powerful new technique that seems ideally suited to the job in hand.

Keywords:

  • siRNA;
  • RNA interference;
  • proteomic;
  • gene silencing