Standard Article

Structure/function of N-glycans

Part 3. Proteomics

3.5. Proteome Diversity

Specialist Review

  1. Miriam V. Dwek1,
  2. Susan Brooks2

Published Online: 15 APR 2005

DOI: 10.1002/047001153X.g305207

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Dwek, M. V. and Brooks, S. 2005. Structure/function of N-glycans. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 3:3.5:64.

Author Information

  1. 1

    University of Westminster, London, UK

  2. 2

    Oxford Brookes University, Oxford, UK

Publication History

  1. Published Online: 15 APR 2005

Abstract

The posttranslational modification of proteins with N-linked glycans is a topic of intense research as the N-linked glycans attached to proteins have been found to have a profound effect on both structure and function of many glycoproteins. This article describes the biosynthesis and function of a range of proteins that are glycosylated with N-linked oligosaccharides.

Keywords:

  • glycosylation;
  • glycan;
  • biosynthesis;
  • structure;
  • function;
  • N-linked