Fundamentals of protein structure and function
Part 3. Proteomics
3.7. Structural Proteomics
Published Online: 15 JAN 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Bradford, J. R., Siepen, J. A. and Westhead, D. R. 2005. Fundamentals of protein structure and function. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 3:3.7:96.
- Published Online: 15 JAN 2005
This chapter describes the steps involved in the formation of three-dimensional structure from amino acid sequence. Proteins have adapted their three-dimensional structures to carry out metabolic and regulatory processes such as enzyme catalysis, molecular transport, signaling, the immune response, and gene expression. To understand the relationship between a protein's structure and function fully, knowledge of that protein's evolutionary history and its interactions is essential. Therefore, we describe the mechanisms by which proteins have evolved. We also describe how molecular recognition drives protein interactions and the types of interaction that take place.
- amino acids;
- protein structure;
- molecular recognition