Large complexes by X-ray methods
Part 3. Proteomics
3.7. Structural Proteomics
Short Specialist Review
Published Online: 15 JUL 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Nissen, P. 2005. Large complexes by X-ray methods. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 3:3.7:99.
- Published Online: 15 JUL 2005
The atomic structures of large complexes such as ribosomes and viruses can be solved by X-ray crystallography. The purification and crystallization, together with data collection and crystallographic phasing, all present unusual problems compared to ordinary high-throughput crystallography. Yet, several examples show how these obstacles can be solved.
- X ray;
- large assembly;
- large complex;
- heavy-atom cluster;
- RNA polymerase