Part 3. Proteomics
3.8. Systems Biology
Short Specialist Review
Published Online: 15 APR 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Shvartsman, S. Y. 2005. EGFR network. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 3:3.8:117.
- Published Online: 15 APR 2005
The epidermal growth factor receptor (EGFR) network is an evolutionarily conserved regulator of epithelial tissues. At this time, we have a relatively good understanding of the mechanisms by which the EGFR network can control the physiology of a single cell. The current challenge, however, is to understand how this network operates in multicellular systems and tissues. To accomplish this, it will be necessary to integrate information from genetic, biochemical, and cellular studies into predictive, quantitative models.
- computational modeling;
- embryonic development