Data collection and analysis in systems biology
Part 3. Proteomics
3.8. Systems Biology
Basic Techniques and Approaches
Published Online: 15 OCT 2004
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Ideker, T. 2004. Data collection and analysis in systems biology. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 3:3.8:118.
- Published Online: 15 OCT 2004
Systems biology studies biological systems by systematically perturbing them (biologically, genetically, or chemically); monitoring the global biological response at the gene, protein, and informational pathway level; integrating these data; and ultimately, formulating mathematical models that describe the structure of the system and its response to individual perturbations. The key technologies that enable systems biology are reviewed with a focus on high-throughput measurement technologies and computational modeling approaches for integrating the resulting large-scale data.
- systems biology;
- functional genomics;
- computer-aided design