Contig mapping and analysis
Part 4. Bioinformatics
4.1. Genome Assembly and Sequencing
Published Online: 15 APR 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Siddiqui, A. and Jones, S. 2005. Contig mapping and analysis. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.1:1.
- Published Online: 15 APR 2005
Physical mapping and the creation of contig maps remains a valuable tool for genomics research. This section describes the methods and techniques used to create contig maps from restriction fragment fingerprint information. It mentions some of the bioinformatics challenges associated with building a high-quality map and points to ongoing research that is attempting to address this problem. This section also illustrates how tiling path clones are chosen from a redundant set of clones.
- physical mapping;
- restriction enzyme fingerprints;
- map contigs;
- tiling path;
- in silico digest;
- Sulston score