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Prokaryotic gene identification in silico

Part 4. Bioinformatics

4.2. Gene Finding and Gene Structure

Introductory Review

  1. Mark Borodovsky,
  2. Rajeev Azad

Published Online: 15 OCT 2004

DOI: 10.1002/047001153X.g402102

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Borodovsky, M. and Azad, R. 2004. Prokaryotic gene identification in silico. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.2:13.

Author Information

  1. Georgia Institute of Technology, Atlanta, GA, USA

Publication History

  1. Published Online: 15 OCT 2004

Abstract

This review covers major lines of development of the gene finding methods for prokaryotic genomes in the last two decades. We describe general ideas behind the algorithms using statistical pattern recognition and dynamic programming, as well as evolutionary relationships between genes and proteins.

Keywords:

  • gene recognition;
  • gene finding in bacterial and archaeal genomes;
  • gene prediction in prokaryotes