Part 4. Bioinformatics
4.2. Gene Finding and Gene Structure
Published Online: 15 JAN 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Huang, X. 2005. Spliced alignment. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.2:15.
- Published Online: 15 JAN 2005
We first describe a dynamic programming algorithm for computing an optimal spliced alignment of a genomic sequence and a cDNA sequence. Then, we present a fast method for dealing with a large set of genomic sequences and a set of cDNA sequences. We also describe methods used in existing spliced alignment programs. We conclude with a discussion of future developments in this area.
- sequence annotation;
- gene finding;
- spliced sites;
- exon–intron boundaries