Searching for genes and biologically related signals in DNA sequences
Part 4. Bioinformatics
4.2. Gene Finding and Gene Structure
Published Online: 15 APR 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Pertea, M. 2005. Searching for genes and biologically related signals in DNA sequences. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.2:16.
- Published Online: 15 APR 2005
A key component of the most successful gene-finding algorithms is the ability to recognize the DNA and RNA sequence patterns that characterize the biological signals that are critical for transcription, splicing, and translation. This chapter discusses some of the most commonly predicted of these signals and the methods that are usually used for their detection. Unfortunately, there is no completely accurate method to identify any of these patterns, although increasingly complex computational techniques have been developed.
- signal detection;
- gene finding;