Gene structure prediction in plant genomes
Part 4. Bioinformatics
4.2. Gene Finding and Gene Structure
Short Specialist Review
Published Online: 15 APR 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Brendel, V. 2005. Gene structure prediction in plant genomes. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.2:21.
- Published Online: 15 APR 2005
Following the completion of the Arabidopsis genome sequence, other plant genome sequences are rapidly accumulating. Computational gene structure annotation in these sequences is a pressing and challenging task. Current approaches are discussed, including ab initio methods, cDNA/EST spliced alignment, and protein spliced alignment. Best results are achieved with combined methods, and human expert annotation will remain necessary to achieve high reliability in large-scale annotation efforts.
- gene prediction;
- spliced alignment;
- ab initio methods;
- splice site prediction