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Transmembrane topology prediction

Part 4. Bioinformatics

4.3. Protein Function and Annotation

Basic Techniques and Approaches

  1. Lukas Käll,
  2. Erik Sonnhammer

Published Online: 15 OCT 2004

DOI: 10.1002/047001153X.g403412

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Käll, L. and Sonnhammer, E. 2004. Transmembrane topology prediction. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.3:38.

Author Information

  1. Karolinska Institutet, Center for Genomics and Bioinformatics, Stockholm, Sweden

Publication History

  1. Published Online: 15 OCT 2004

Abstract

We describe the most popular transmembrane topology predictors and highlight their advantages and shortcomings. We also review different benchmark studies on transmembrane predictors.

Keywords:

  • transmembrane proteins;
  • topology prediction;
  • machine learning;
  • bioinformatics;
  • benchmarking