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Chromosome phylogeny

Part 4. Bioinformatics

4.4. Comparative Analysis and Phylogeny

Short Specialist Review

  1. Guillaume Bourque

Published Online: 15 NOV 2005

DOI: 10.1002/047001153X.g404310

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Bourque, G. 2005. Chromosome phylogeny. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.4:49.

Author Information

  1. Genome Institute of Singapore, Singapore

Publication History

  1. Published Online: 15 NOV 2005

Abstract

Recent release of several detailed whole-genome sequences and maps has allowed the analysis of the evolutionary history of large-scale rearrangements that have shaped the genome architecture of these modern organisms. Models and algorithms that have been developed to tackle this question are reviewed and some of the initial noteworthy findings are summarized. Limitations of the current techniques and future prospects are also presented. Finally, it is proposed that powerful new insights in this area will probably come from in-depth analyses of evolutionary breakpoint regions.

Keywords:

  • chromosome evolution;
  • genome rearrangements;
  • breakpoint regions