Part 4. Bioinformatics
4.4. Comparative Analysis and Phylogeny
Short Specialist Review
Published Online: 15 NOV 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Bourque, G. 2005. Chromosome phylogeny. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.4:49.
- Published Online: 15 NOV 2005
Recent release of several detailed whole-genome sequences and maps has allowed the analysis of the evolutionary history of large-scale rearrangements that have shaped the genome architecture of these modern organisms. Models and algorithms that have been developed to tackle this question are reviewed and some of the initial noteworthy findings are summarized. Limitations of the current techniques and future prospects are also presented. Finally, it is proposed that powerful new insights in this area will probably come from in-depth analyses of evolutionary breakpoint regions.
- chromosome evolution;
- genome rearrangements;
- breakpoint regions