Part 4. Bioinformatics
4.5. Computational Methods for High-throughput Genetic Analysis: Expression Profiling
Published Online: 15 NOV 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Dobbin, K. K. and Simon, R. M. 2005. Experimental design. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.5:52.
- Published Online: 15 NOV 2005
Experimental design issues for dual-label and single-label microarray experiments are discussed, including identification of research objectives, avoidance of confounding, allotment of samples to arrays, and dyes in dual-label experiments, dye bias, pooling RNA before labeling, and determination of the number of arrays required to achieve the study objectives.
- experimental design;
- sample size;
- dye bias;
- reference sample