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Complexity in biological structures and systems

Part 4. Bioinformatics

4.6. Methods for Structure Analysis and Prediction

Specialist Review

  1. Arthur M. Lesk

Published Online: 15 NOV 2005

DOI: 10.1002/047001153X.g406206

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Lesk, A. M. 2005. Complexity in biological structures and systems. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.6:69.

Author Information

  1. The Pennsylvania State University, University Park, PA, USA

Publication History

  1. Published Online: 15 NOV 2005

Abstract

Complexity and related concepts are important for understanding life processes as revealed in the new high-throughput data streams. Formal analysis of complexity is less advanced in biology than in certain other fields, including mathematics, physics, and computer science. This article offers an introduction to complexity for biologists, with emphasis on explaining the concepts and results from other fields applicable to understanding living systems at the molecular level. Many of the questions raised are subjects of current research.

Keywords:

  • systems biology;
  • randomness and entropy of sequences;
  • protein structure;
  • network structure and dynamics;
  • computational complexity;
  • predictability;
  • chaos