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The Protein Data Bank (PDB) and the Worldwide PDB http://www.wwpdb.org

Part 4. Bioinformatics

4.6. Methods for Structure Analysis and Prediction

Short Specialist Review

  1. Helen Berman1,
  2. Haruki Nakamura2,
  3. Kim Henrick3

Published Online: 15 JAN 2005

DOI: 10.1002/047001153X.g406303

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

How to Cite

Berman, H., Nakamura, H. and Henrick, K. 2005. The Protein Data Bank (PDB) and the Worldwide PDB http://www.wwpdb.org. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.6:71.

Author Information

  1. 1

    The State University of New Jersey, NJ, USA

  2. 2

    Osaka University, Osaka, Japan

  3. 3

    MSD-European Bioinformatics Institute, Hinxton, UK

Publication History

  1. Published Online: 15 JAN 2005

Abstract

The Protein Data Bank is the primary source of information on the 3D structure of biological macromolecules. The PDB is a rich source of structural information that holds significant promise for the pharmaceutical and biotechnology industries in the search for new drugs, and the efforts to understand the mechanism of disease. The PDB is managed by the wwPDB (http://www.wwpdb.org), and the wwPDB members enable science worldwide by providing resources to improve our understanding of structure-function relationships in biological systems.

Keywords:

  • macromolecular structure;
  • data management;
  • data uniformity;
  • data validation