Threading for protein-fold recognition
Part 4. Bioinformatics
4.6. Methods for Structure Analysis and Prediction
Short Specialist Review
Published Online: 15 APR 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Lin, K. 2005. Threading for protein-fold recognition. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.6:72.
- Published Online: 15 APR 2005
Protein three-dimensional structures, which provide vital biological information, can often be solved using X-ray crystallography and NMR techniques (Thornton et al., 1999; Orengo et al., 2001). These structure-solving techniques have been greatly improved in the last two decades. However, protein sequences from large-scale gene-sequencing projects are emerging at extraordinary rates. The gap between the number of known protein sequences and the known protein structures is continuously enlarging. Methods of predicting protein structure from its amino acid sequence are therefore of great importance to many biological researches.
- structure prediction;
- scoring function;