Design of KEGG and GO
Part 4. Bioinformatics
4.8. Modern Programming Paradigms in Biology
Short Specialist Review
Published Online: 15 APR 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
How to Cite
Kanehisa, M. 2005. Design of KEGG and GO. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. 4:4.8:101.
- Published Online: 15 APR 2005
The complete genome sequence contains the information about a repertoire of genes, which would enable the understanding of higher-level complexity of cellular functions and organismic phenotypes. The process of genome annotation, in which individual gene functions are assigned, should then be coupled with capturing collective features of higher-level biological systems. The two resources, KEGG (Kyoto Encyclopedia of Genes and Genomes) and GO (Gene Ontology), provide facilities for computational mapping of individual gene functions to higher-level systemic functions with different concepts and implementations.
- genome annotation;
- microarray analysis;
- network analysis;
- metabolic pathway;
- chemical genomics